Efficacy and safety of treating benign prostatic hyperplasia with Finasteride
Prostate adenoma: what it is and how the threat manifests itself? A prostate adenoma is an incredibly unpleasant disease. Unfortunately, the risks of facing it are very high, as it is one of the most common male diseases. How dangerous is this illness, how to treat it, and is there a way to minimize the risk of getting sick?
Characteristics and epidemiology of benign prostatic hyperplasia A prostate adenoma is benign hyperplasia, that is, the growth of small glands located in the tissues of the bladder neck. The disease develops gradually. Firstly, a small nodule is formed in the tissues of the gland, which increases over time. Because of this, prostate gland blocks the clearance of the urinary channel, preventing the normal outflow of urine. Prostate adenoma itself is not life-threatening, but the symptoms of this disorder are extremely unpleasant, and sometimes even painful. At the later stages, adenoma causes kidney disorders, which carries a severe health risk. By the way, today, professionals often use the term ""benign prostatic hyperplasia" to denote this disease, but patients are accustomed to calling it adenoma. A prostate adenoma is not a rare diagnosis. This disease is diagnosed in 30-40% of men over 50 years and 75-90% over 65 years. In fact, 9 out of 10 men face it sooner or later.
Causes of disease
We don't know yet the certain causes of adenoma. Some studies in Australia confirm that low sexual activity is a risk factor. Nevertheless, this disease is also diagnosed in those who live an active sex life. Hormonal disorders can provoke the development of adenoma. Risk factors include atherosclerosis, overweight and obesity, age-related changes, stress, and adverse environmental conditions.
Symptoms and signs of benign prostatic hyperplasia The danger of prostate adenoma is that the disease is almost asymptotically. Sometimes, even patients with a relatively large tumor don't feel any inconvenience. Even if any symptoms are present, they can come and go, which creates the misleading impression that the situation has returned to normal. The first signs of benign prostatic hyperplasia arise when enlarged prostate obstructs the outflow of urine. This stage is characterized by such manifestations as frequent urination at night, urination difficulty, weakening the strength of the urine stream and after dribble. Over time, the condition worsens —patient experiences pain during urination, incontinence, erectile dysfunction, weakness, nausea, lack of appetite, and sudden weight loss.
Forms of prostate adenoma
There are several stages of prostate adenoma:
- Stage 1 is the beginning of the disease, when the symptoms may be mild. The most characteristic features are changes in the process of urination: the intensity of the outflow decreases and the urges become more frequent (sometimes you have to get up from 5 to 10 times a night). Some note that sometimes there is no way to restrain the urge. However, even in case of such symptoms, patients often refuse to go to the doctor, believing that these changes don't deserve attention. Without proper therapy, the disease quickly enters the second stage.
- At the stage 2, the outflow of urine is seriously hampered, and the liquid constantly accumulates in the bladder. This is manifested by a constant feeling of incomplete discharge. Urination becomes a problem and sometimes takes a long time. Urine stretches the bladder and slowly causes atrophic changes, which, in turn, lead to kidney disorder. Other symptoms of stage 2 prostate adenoma include dry mouth, increased thirst, and irritability.
- When the disease enters the third stage, it becomes impossible to ignore the signs of prostate adenoma. Patients develop renal failure and bladder disorders. This is fraught with urinary infections, kidney stones, and incontinence. Urination requires strong muscle tension and becomes very painful; patients often notice blood in the urine. The urge to urinate is so frequent that it becomes impossible to lead a normal life. The late stage of prostate adenoma affects the general state of health. Patients suffer from constant thirst and dry mouth, experience breakdowns, and become extremely irritable. They increasingly suffer from attacks of nausea and vomiting and lack of appetite.
Consequences of the disease
Prostate adenoma never passes without medical intervention. If the process began, sooner or later, it will end in the third stage and serious health problems. In addition, neglected prostate adenoma dramatically increases the risk of hydronephrosis — a disease in which the kidneys are filled with urine.
Treatment of prostate adenoma with Proscar
Finasteride is included in the group of drugs intended for the treatment of benign prostatic hypertrophy. Finasteride is the main active component of the drug, which represents a 5α-reductase inhibitor (type II). Finasteride substance represents an intracellular enzyme, through which testosterone is converted into androgen dihydrotestosterone (the main reason for this type of prostate hyperplasia), which is an androgen of higher activity. Proscar cost allows anyone get the quality and effective treatment.
Finasteride can effectively reduce the level of dihydrotestosterone (both circulating and intra-static). To buy Proscar helps to reduce urinary retention in an acute form more than twice after 4 years of treatment. For the same period, the risk of surgery decreases by 50%. It also leads to the regression in size of the prostate by 1/5, while significantly increasing the speed of urine outflow. The risks of further progression of the disease are reduced by 67%. Proscar price is rather low, so the treatment should be started as soon as possible. Research conducted in Australia showed that regular intake of this medicine for benign hypertrophy of the prostate reduces.
Way of use and dosage
Generic Proscar is intended for regular long-term use. The recommended dosage is 5 mg (1 tablet) once a day, preferably at the same time of the day.
According to Proscar online indications, the drug can be taken regardless of the mealtime.
You can take the drug in combination with Doxazosin (alpha-blocker). The course of treatment with Proscar pills can last for many months, or even several years. The exact duration of treatment with Proscar without prescription depends on the effectiveness of the drug, which is determined individually by means of diagnostic studies. Efficiency evaluation of cheap Proscar is carried out at least once every 6 months.